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Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions

OBJECTIVE: The immune response to invasive carcinoma has been the focus of published work, but little is known about the adaptive immune response to bronchial premalignant lesions (PMLs), precursors of lung squamous cell carcinoma. This study was designed to characterize the T cell receptor (TCR) re...

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Detalles Bibliográficos
Autores principales: Maoz, Asaf, Merenstein, Carter, Koga, Yusuke, Potter, Austin, Gower, Adam C, Liu, Gang, Zhang, Sherry, Liu, Hanqiao, Stevenson, Christopher, Spira, Avrum, Reid, Mary E, Campbell, Joshua D, Mazzilli, Sarah A, Lenburg, Marc E, Beane, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477334/
https://www.ncbi.nlm.nih.gov/pubmed/34580161
http://dx.doi.org/10.1136/jitc-2021-002647