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Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions
OBJECTIVE: The immune response to invasive carcinoma has been the focus of published work, but little is known about the adaptive immune response to bronchial premalignant lesions (PMLs), precursors of lung squamous cell carcinoma. This study was designed to characterize the T cell receptor (TCR) re...
Autores principales: | Maoz, Asaf, Merenstein, Carter, Koga, Yusuke, Potter, Austin, Gower, Adam C, Liu, Gang, Zhang, Sherry, Liu, Hanqiao, Stevenson, Christopher, Spira, Avrum, Reid, Mary E, Campbell, Joshua D, Mazzilli, Sarah A, Lenburg, Marc E, Beane, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477334/ https://www.ncbi.nlm.nih.gov/pubmed/34580161 http://dx.doi.org/10.1136/jitc-2021-002647 |
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