Blocking Placental Class G Immunoglobulin Transfer Prevents NMDA Receptor Antibody Effects in Newborn Mice

BACKGROUND AND OBJECTIVES: To determine in a mouse model whether neonatal Fc receptor (FcRn) blockade prevents the placental transfer of class G immunoglobulin (IgG) derived from patients with anti-NMDA receptor (NMDAR) encephalitis and their pathogenic effects on the fetuses and offspring. METHODS:...

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Detalles Bibliográficos
Autores principales: García-Serra, Anna, Radosevic, Marija, Ríos, José, Aguilar, Esther, Maudes, Estibaliz, Landa, Jon, Sabater, Lidia, Martinez-Hernandez, Eugenia, Planagumà, Jesús, Dalmau, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477376/
https://www.ncbi.nlm.nih.gov/pubmed/34580181
http://dx.doi.org/10.1212/NXI.0000000000001061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477376/
https://www.ncbi.nlm.nih.gov/pubmed/34580181
http://dx.doi.org/10.1212/NXI.0000000000001061

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