Cargando…

Blocking Placental Class G Immunoglobulin Transfer Prevents NMDA Receptor Antibody Effects in Newborn Mice

BACKGROUND AND OBJECTIVES: To determine in a mouse model whether neonatal Fc receptor (FcRn) blockade prevents the placental transfer of class G immunoglobulin (IgG) derived from patients with anti-NMDA receptor (NMDAR) encephalitis and their pathogenic effects on the fetuses and offspring. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	García-Serra, Anna, Radosevic, Marija, Ríos, José, Aguilar, Esther, Maudes, Estibaliz, Landa, Jon, Sabater, Lidia, Martinez-Hernandez, Eugenia, Planagumà, Jesús, Dalmau, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477376/ https://www.ncbi.nlm.nih.gov/pubmed/34580181 http://dx.doi.org/10.1212/NXI.0000000000001061

Ejemplares similares

Allosteric Modulation of NMDARs Reverses Patients' Autoantibody Effects in Mice
por: Radosevic, Marija, et al.
Publicado: (2021)

Placental transfer of NMDAR antibodies causes reversible alterations in mice
por: García-Serra, Anna, et al.
Publicado: (2020)

Clinical significance of Kelch-like protein 11 antibodies
por: Maudes, Estibaliz, et al.
Publicado: (2020)

Cellular investigations with human antibodies associated with the anti-IgLON5 syndrome
por: Sabater, Lidia, et al.
Publicado: (2016)

Pregnancy outcomes in anti-NMDA receptor encephalitis: Case series
por: Joubert, Bastien, et al.
Publicado: (2020)

Mouse model of anti-NMDA receptor post–herpes simplex encephalitis
por: Linnoila, Jenny, et al.
Publicado: (2018)

The diagnosis of anti-LGI1 encephalitis varies with the type of immunodetection assay and sample examined
por: Muñoz-Sánchez, Guillermo, et al.
Publicado: (2022)

Seizure-related 6 homolog like 2 autoimmunity: Neurologic syndrome and antibody effects
por: Landa, Jon, et al.
Publicado: (2020)

Thymoma and Autoimmune Encephalitis: Clinical Manifestations and Antibodies
por: Guasp, Mar, et al.
Publicado: (2021)

Patients’ IgLON5 autoantibodies interfere with IgLON5-protein interactions
por: Landa, Jon, et al.
Publicado: (2023)

Corrigendum: Patients’ IgLON5 autoantibodies interfere with IgLON5–protein interactions
por: Landa, Jon, et al.
Publicado: (2023)

Clinical features of seronegative, but CSF antibody-positive, anti-NMDA receptor encephalitis
por: Guasp, Mar, et al.
Publicado: (2020)

In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction
por: Manto, Mario, et al.
Publicado: (2010)

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis
por: Balu, Ramani, et al.
Publicado: (2019)

Antibody Repertoire in Paraneoplastic Cerebellar Degeneration and Small Cell Lung Cancer
por: Sabater, Lidia, et al.
Publicado: (2013)

Antibodies to Inhibitory Synaptic Proteins in Neurological Syndromes Associated with Glutamic Acid Decarboxylase Autoimmunity
por: Gresa-Arribas, Nuria, et al.
Publicado: (2015)

Considerations of psychotic symptomatology in anti‐NMDA encephalitis: Similarity to cycloid psychosis
por: Giné Servén, Eloi, et al.
Publicado: (2019)

Novel Antibacterial and Toughened Carbon-Fibre/Epoxy Composites by the Incorporation of TiO(2) Nanoparticles Modified Electrospun Nanofibre Veils
por: Monteserín, Cristina, et al.
Publicado: (2019)

Limitations of a Commercial Assay as Diagnostic Test of Autoimmune Encephalitis
por: Ruiz-García, Raquel, et al.
Publicado: (2021)

Caveats and Pitfalls of SOX1 Autoantibody Testing With a Commercial Line Blot Assay in Paraneoplastic Neurological Investigations
por: Ruiz-García, Raquel, et al.
Publicado: (2019)

Effect of Different Types of Electrospun Polyamide 6 Nanofibres on the Mechanical Properties of Carbon Fibre/Epoxy Composites
por: Monteserín, Cristina, et al.
Publicado: (2018)

TiO(2)-Doped Electrospun Nanofibrous Membrane for Photocatalytic Water Treatment
por: Blanco, Miren, et al.
Publicado: (2019)

Passive Immunity to Vaccinia in Newborns: I. Placental Transmission of Antibodies
por: Kempe, C. Henry
Publicado: (1952)

Placental Transmission of Human Parvovirus 4 in Newborns with Hydrops, Taiwan
por: Chen, Mao-Yuan, et al.
Publicado: (2011)

Micronucleated Erythrocytes in Newborn Rats Exposed to Raltegravir Placental Transfer
por: Torres-Mendoza, Blanca Miriam, et al.
Publicado: (2014)

Providing a Placental Transfusion in Newborns Who Need Resuscitation
por: Katheria, Anup C., et al.
Publicado: (2017)

Suitability of Placental Blood Samples of Newborns for Pre-Transfusion Testing
por: Alissa, Rana, et al.
Publicado: (2021)

IMMUNOGLOBULINS IN NZB/BL MICE : I. SERUM IMMUNOGLOBULIN LEVELS AND IMMUNOGLOBULIN CLASS OF ERYTHROCYTE AUTOANTIBODY
por: Warner, Noel L., et al.
Publicado: (1968)

THE IMMUNOGLOBULINS OF MICE : V. THE METABOLIC (CATABOLIC) PROPERTIES OF FIVE IMMUNOGLOBULIN CLASSES
por: Fahey, John L., et al.
Publicado: (1965)

Immunoglobulin class-switch recombination deficiencies
por: Durandy, Anne, et al.
Publicado: (2012)

Algorithm to improve the diagnosis of paraneoplastic neurological syndromes associated with SOX1 antibodies
por: Arnaldos-Pérez, Cristina, et al.
Publicado: (2023)

S164. HIPPOCAMPAL CONNECTIVITY IN YOUTH WITH SCHIZOPHRENIA: COMPARISON WITH PATIENTS WITH NMDA RECEPTOR ENCEPHALITIS AND HEALTHY VOLUNTEERS
por: Sugranyes, Gisela, et al.
Publicado: (2020)

T cell regulation of immunoglobulin class expression in the antibody response to trinitrophenyl-ficoll. Evidence for T cell enhancement of the immunoglobulin class switch
Publicado: (1982)

Newborn Body Fat: Associations with Maternal Metabolic State and Placental Size
por: Friis, Camilla M., et al.
Publicado: (2013)

Correlation of placental microbiota with fetal macrosomia and clinical characteristics in mothers and newborns
por: Zheng, Jia, et al.
Publicado: (2017)

Paraneoplastic cerebellar ataxia and antibodies to metabotropic glutamate receptor 2
por: Ruiz-García, Raquel, et al.
Publicado: (2019)

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse
Publicado: (1996)

Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns
por: Assi, Emma, et al.
Publicado: (2020)

Placental DNA methylation changes and the early prediction of autism in full-term newborns
por: Bahado-Singh, Ray O., et al.
Publicado: (2021)

The effect of placental transfusion on hemodynamics in premature newborns: a randomized controlled trial
por: Farag, Marwa Mohamed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u1n3dhoa5ub1diqlu1bocvjh0e