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Transferrable protection by gut microbes against STING-associated lung disease

STING modulates immunity by responding to bacterial and endogenous cyclic dinucleotides (CDNs). Humans and mice with STING gain-of-function mutations develop a syndrome known as STING-associated vasculopathy with onset in infancy (SAVI), which is characterized by inflammatory or fibrosing lung disea...

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Detalles Bibliográficos
Autores principales: Platt, Derek J., Lawrence, Dylan, Rodgers, Rachel, Schriefer, Lawrence, Qian, Wei, Miner, Cathrine A., Menos, Amber M., Kennedy, Elizabeth A., Peterson, Stefan T., Stinson, W. Alexander, Baldridge, Megan T., Miner, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477380/
https://www.ncbi.nlm.nih.gov/pubmed/33979608
http://dx.doi.org/10.1016/j.celrep.2021.109113