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The impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemma
Cationic polymers have been widely studied for non-viral gene delivery due to their ability to bind genetic material and to interact with cellular membranes. However, their charged nature carries the risk of increased cytotoxicity and interaction with serum proteins, limiting their potential in vivo...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477462/ https://www.ncbi.nlm.nih.gov/pubmed/34579715 http://dx.doi.org/10.1186/s12951-021-00994-2 |