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Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker

BACKGROUND: Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle. In cancer cells TK1 is upregulated and excess T...

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Detalles Bibliográficos
Autores principales: Wang, Liya, Sharif, Hanan, Saellström, Sara, Rönnberg, Henrik, Eriksson, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477555/
https://www.ncbi.nlm.nih.gov/pubmed/34579716
http://dx.doi.org/10.1186/s12917-021-03030-5