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High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs

BACKGROUND: It is established that protein-coding exons are preferentially localized in nucleosomes. To examine whether the same is true for non-coding exons, we analysed nucleosome occupancy in and adjacent to internal exons in genes encoding long non-coding RNAs (lncRNAs) in human CD4+ T cells and...

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Detalles Bibliográficos
Autores principales: Dey, Pinki, Mattick, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477579/
https://www.ncbi.nlm.nih.gov/pubmed/34579770
http://dx.doi.org/10.1186/s13072-021-00419-2