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The importance of endothelial protection: the emerging role of defibrotide in reversing endothelial injury and its sequelae

Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS), a potentially life-threatening complication of hematopoietic cell transplantation (HCT), results from prolonged sinusoidal endothelial cell activation and profound endothelial cell damage, with sequelae. Defibrotide, the only...

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Detalles Bibliográficos
Autores principales: Richardson, Paul G., Palomo, Marta, Kernan, Nancy A., Hildebrandt, Gerhard C., Chao, Nelson, Carreras, Enric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477726/
https://www.ncbi.nlm.nih.gov/pubmed/34584241
http://dx.doi.org/10.1038/s41409-021-01383-x