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The importance of endothelial protection: the emerging role of defibrotide in reversing endothelial injury and its sequelae
Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS), a potentially life-threatening complication of hematopoietic cell transplantation (HCT), results from prolonged sinusoidal endothelial cell activation and profound endothelial cell damage, with sequelae. Defibrotide, the only...
Autores principales: | Richardson, Paul G., Palomo, Marta, Kernan, Nancy A., Hildebrandt, Gerhard C., Chao, Nelson, Carreras, Enric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477726/ https://www.ncbi.nlm.nih.gov/pubmed/34584241 http://dx.doi.org/10.1038/s41409-021-01383-x |
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