A Single Animal Species-Based Prediction of Human Clearance and First-in-Human Dose of Monoclonal Antibodies: Beyond Monkey

These days, there is a lot of emphasis on the prediction of human clearance (CL) from a single species for monoclonal antibodies (mabs). Many studies indicate that monkey is the most suitable species for the prediction of human clearance for mabs. However, it is not well established if rodents (mous...

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Detalles Bibliográficos
Autor principal: Mahmood, Iftekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477747/
https://www.ncbi.nlm.nih.gov/pubmed/34562983
http://dx.doi.org/10.3390/antib10030035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477747/
https://www.ncbi.nlm.nih.gov/pubmed/34562983
http://dx.doi.org/10.3390/antib10030035

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