Activation of the ATF6 (Activating Transcription Factor 6) Signaling Pathway in Neurons Improves Outcome After Cardiac Arrest in Mice

BACKGROUND: Ischemia/reperfusion injury impairs proteostasis, and triggers adaptive cellular responses, such as the unfolded protein response (UPR), which functions to restore endoplasmic reticulum homeostasis. After cardiac arrest (CA) and resuscitation, the UPR is activated in various organs inclu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yuntian, Li, Ran, Yu, Shu, Zhao, Qiang, Wang, Zhuoran, Sheng, Huaxin, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477867/
https://www.ncbi.nlm.nih.gov/pubmed/34111943
http://dx.doi.org/10.1161/JAHA.120.020216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477867/
https://www.ncbi.nlm.nih.gov/pubmed/34111943
http://dx.doi.org/10.1161/JAHA.120.020216

Ejemplares similares