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Membrane protein-chimeric liposome-mediated delivery of triptolide for targeted hepatocellular carcinoma therapy

Triptolide (TPL) is a diterpenoid triepoxide with broad antitumor efficacy, while lack of mechanism of action, severe systemic toxicity, and poor water solubility of TPL limited its usage. To unveil the mechanism of action and improve the pharmaceutical properties of TPL, here we explored the molecu...

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Detalles Bibliográficos
Autores principales: Zheng, Yanwen, Kong, Fanhua, Liu, Songyang, Liu, Xi, Pei, Dongni, Miao, Xiongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477919/
https://www.ncbi.nlm.nih.gov/pubmed/34569906
http://dx.doi.org/10.1080/10717544.2021.1983072