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Increased α‐tocopherol metabolism in horses with equine neuroaxonal dystrophy

BACKGROUND: Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder associated with a vitamin E deficiency within the first year of life. Vitamin E consists of 8 isoforms metabolized by the CYP4F2 enzyme. No antemortem diagnostic tes...

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Detalles Bibliográficos
Autores principales: Hales, Erin N., Habib, Hadi, Favro, Gianna, Katzman, Scott, Sakai, R. Russell, Marquardt, Sabin, Bordbari, Matthew H., Ming‐Whitfield, Brittni, Peterson, Janel, Dahlgren, Anna R., Rivas, Victor, Ramirez, Carolina Alanis, Peng, Sichong, Donnelly, Callum G., Dizmang, Bobbi‐Sue, Kallenberg, Angelica, Grahn, Robert, Miller, Andrew D., Woolard, Kevin, Moeller, Benjamin, Puschner, Birgit, Finno, Carrie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478026/
https://www.ncbi.nlm.nih.gov/pubmed/34331715
http://dx.doi.org/10.1111/jvim.16233