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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo
During embryogenesis, waves of hematopoietic progenitors develop from hemogenic endothelium (HE) prior to the emergence of self-renewing hematopoietic stem cells (HSCs). Although previous studies have shown that yolk-sac-derived erythromyeloid progenitors and HSCs emerge from distinct populations of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478150/ https://www.ncbi.nlm.nih.gov/pubmed/34525376 http://dx.doi.org/10.1016/j.celrep.2021.109675 |