Cargando…

Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

During embryogenesis, waves of hematopoietic progenitors develop from hemogenic endothelium (HE) prior to the emergence of self-renewing hematopoietic stem cells (HSCs). Although previous studies have shown that yolk-sac-derived erythromyeloid progenitors and HSCs emerge from distinct populations of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dignum, Tessa, Varnum-Finney, Barbara, Srivatsan, Sanjay R., Dozono, Stacey, Waltner, Olivia, Heck, Adam M., Ishida, Takashi, Nourigat-McKay, Cynthia, Jackson, Dana L., Rafii, Shahin, Trapnell, Cole, Bernstein, Irwin D., Hadland, Brandon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478150/ https://www.ncbi.nlm.nih.gov/pubmed/34525376 http://dx.doi.org/10.1016/j.celrep.2021.109675

Ejemplares similares

Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics
por: Hadland, Brandon, et al.
Publicado: (2022)

Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution
por: Ishida, Takashi, et al.
Publicado: (2023)

Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage
por: Zhao, Shizheng, et al.
Publicado: (2022)

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells
por: Uenishi, Gene I., et al.
Publicado: (2018)

Specification and function of hemogenic endothelium during embryogenesis
por: Gritz, Emily, et al.
Publicado: (2016)

Cell cycle dynamics and complement expression distinguishes mature haematopoietic subsets arising from hemogenic endothelium
por: Zape, Joan P., et al.
Publicado: (2017)

HoxA3 is an apical regulator of hemogenic endothelium
por: Iacovino, Michelina, et al.
Publicado: (2010)

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells
por: Monteiro, Rui, et al.
Publicado: (2016)

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells
por: Hadland, Brandon K., et al.
Publicado: (2017)

Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition
por: Lizama, Carlos O., et al.
Publicado: (2015)

Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro
por: Garcia-Alegria, Eva, et al.
Publicado: (2018)

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition
por: Kang, HyunJun, et al.
Publicado: (2018)

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta
por: Chen, Inn-Inn, et al.
Publicado: (2016)

Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium
por: Lie-A-Ling, Michael, et al.
Publicado: (2018)

HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development
por: Teichweyde, Nadine, et al.
Publicado: (2018)

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta
por: Zamir, Lyad, et al.
Publicado: (2017)

Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation
por: Cortes, Mauricio, et al.
Publicado: (2015)

A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17
por: Clarke, Raedun L., et al.
Publicado: (2015)

The hemogenic endothelium: a critical source for the generation of PSC-derived hematopoietic stem and progenitor cells
por: Lange, Lucas, et al.
Publicado: (2021)

Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium
por: Jeon, Soo-Been, et al.
Publicado: (2023)

Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium
por: Guo, Yuhan, et al.
Publicado: (2020)

LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage
por: Lee, Lydia K., et al.
Publicado: (2016)

SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis
por: Jung, Ho Sun, et al.
Publicado: (2021)

Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation
por: Saxena, Shobhit, et al.
Publicado: (2016)

Cytokine-free directed differentiation of human pluripotent stem cells efficiently produces hemogenic endothelium with lymphoid potential
por: Galat, Yekaterina, et al.
Publicado: (2017)

In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation
por: Garcia-Alegria, Eva, et al.
Publicado: (2021)

SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways
por: Jung, Ho Sun, et al.
Publicado: (2023)

Angiocrine endothelium: from physiology to cancer
por: Pasquier, Jennifer, et al.
Publicado: (2020)

Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2
por: Soto, Rebecca A., et al.
Publicado: (2021)

Single-cell transcriptome analysis of embryonic and adult endothelial cells allows to rank the hemogenic potential of post-natal endothelium
por: Adamov, Artem, et al.
Publicado: (2022)

Lymphoid Lineage γδ T Cells Were Successfully Generated from Human Pluripotent Stem Cells via Hemogenic Endothelium
por: Jeon, Soo-Been, et al.
Publicado: (2022)

Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes
por: Howell, Elizabeth D., et al.
Publicado: (2021)

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification
por: Maurya, Shailendra, et al.
Publicado: (2021)

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes
por: Palpant, Nathan J., et al.
Publicado: (2015)

Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells
por: Dallas, Mari H., et al.
Publicado: (2005)

Atrial myxomas arise from multipotent cardiac stem cells
por: Scalise, Mariangela, et al.
Publicado: (2020)

Hemogenic endocardium contributes to transient definitive hematopoiesis
por: Nakano, Haruko, et al.
Publicado: (2013)

Isolation of Murine Embryonic Hemogenic Endothelial Cells
por: Fang, Jennifer S., et al.
Publicado: (2016)

CD34(dim) cells identified as pluripotent stem cell‐derived definitive hemogenic endothelium purified using bone morphogenetic protein 4
por: Jeon, Soo‐Been, et al.
Publicado: (2022)

SAHA Enhances Differentiation of CD34+CD45+ Hematopoietic Stem and Progenitor Cells from Pluripotent Stem Cells Concomitant with an Increase in Hemogenic Endothelium
por: Shim, Seon-Hui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_05f8rdcg688e8hqgdf9no92o4e