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Drug Repurposing for Targeting Acute Leukemia With KMT2A (MLL)—Gene Rearrangements

The treatment failure rates of acute leukemia with rearrangements of the Mixed Lineage Leukemia (MLL) gene highlight the need for novel therapeutic approaches. Taking into consideration the limitations of the current therapies and the advantages of novel strategies for drug discovery, drug repurposi...

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Detalles Bibliográficos
Autores principales: Tsakaneli, Alexia, Williams, Owen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478155/
https://www.ncbi.nlm.nih.gov/pubmed/34594227
http://dx.doi.org/10.3389/fphar.2021.741413