Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV

Osteogenesis imperfecta (OI) type XIV is a rare recessive bone disorder characterized by variable degree of severity associated to osteopenia. It is caused by mutations in TMEM38B encoding for the trimeric intracellular cation channel TRIC-B, specific for potassium and ubiquitously present in the en...

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Detalles Bibliográficos
Autores principales: Leoni, Laura, Tonelli, Francesca, Besio, Roberta, Gioia, Roberta, Moccia, Francesco, Rossi, Antonio, Forlino, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478202/
https://www.ncbi.nlm.nih.gov/pubmed/34582479
http://dx.doi.org/10.1371/journal.pone.0257254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478202/
https://www.ncbi.nlm.nih.gov/pubmed/34582479
http://dx.doi.org/10.1371/journal.pone.0257254

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