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Snail regulation in fibroblast-like synoviocytes by a histone deacetylase or glycogen synthase kinase inhibitor affects cell proliferation and gene expression

BACKGROUND: Snail has been linked to the pathogenesis of rheumatoid arthritis (RA). We plan to investigate the regulation of Snail in response to TNF-α, histone acetylation, and glycogen synthase kinase-3 (GSK)-3 inhibition in fibroblast-like synoviocytes (FLSs). METHODS: FLSs from rats with collage...

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Detalles Bibliográficos
Autores principales: Shen, Po-Chuan, Chang, Po-Chun, Hsieh, Jeng-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478242/
https://www.ncbi.nlm.nih.gov/pubmed/34582486
http://dx.doi.org/10.1371/journal.pone.0257839