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Snail regulation in fibroblast-like synoviocytes by a histone deacetylase or glycogen synthase kinase inhibitor affects cell proliferation and gene expression
BACKGROUND: Snail has been linked to the pathogenesis of rheumatoid arthritis (RA). We plan to investigate the regulation of Snail in response to TNF-α, histone acetylation, and glycogen synthase kinase-3 (GSK)-3 inhibition in fibroblast-like synoviocytes (FLSs). METHODS: FLSs from rats with collage...
Autores principales: | Shen, Po-Chuan, Chang, Po-Chun, Hsieh, Jeng-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478242/ https://www.ncbi.nlm.nih.gov/pubmed/34582486 http://dx.doi.org/10.1371/journal.pone.0257839 |
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