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Neuroprotective Action of Multitarget 7-Aminophenanthridin-6(5H)-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells

[Image: see text] Neurodegenerative diseases have been associated with brain metal accumulation, which produces oxidative stress (OS), matrix metalloproteinases (MMPs) induction, and neuronal cell death. Several metals have been reported to downregulate both the nuclear factor erythroid 2-related fa...

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Detalles Bibliográficos
Autores principales: Moyano, Paula, Vicente-Zurdo, David, Blázquez-Barbadillo, Cristina, Menéndez, J. Carlos, González, Juan F., Rosales-Conrado, Noelia, del Pino, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478279/
https://www.ncbi.nlm.nih.gov/pubmed/34460227
http://dx.doi.org/10.1021/acschemneuro.1c00333