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Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

Collagen-rich tissues have poor reparative capacity that predisposes to common age-related disorders such as osteoporosis and osteoarthritis. We used in vivo pulsed SILAC labelling to quantify new protein incorporation into cartilage, bone, and skin of mice across the healthy life course. We report...

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Detalles Bibliográficos
Autores principales: Ariosa-Morejon, Yoanna, Santos, Alberto, Fischer, Roman, Davis, Simon, Charles, Philip, Thakker, Rajesh, Wann, Angus KT, Vincent, Tonia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478409/
https://www.ncbi.nlm.nih.gov/pubmed/34581667
http://dx.doi.org/10.7554/eLife.66635