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Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling
Collagen-rich tissues have poor reparative capacity that predisposes to common age-related disorders such as osteoporosis and osteoarthritis. We used in vivo pulsed SILAC labelling to quantify new protein incorporation into cartilage, bone, and skin of mice across the healthy life course. We report...
Autores principales: | Ariosa-Morejon, Yoanna, Santos, Alberto, Fischer, Roman, Davis, Simon, Charles, Philip, Thakker, Rajesh, Wann, Angus KT, Vincent, Tonia L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478409/ https://www.ncbi.nlm.nih.gov/pubmed/34581667 http://dx.doi.org/10.7554/eLife.66635 |
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