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Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

High-throughput genomics of SARS-CoV-2 is essential to characterize virus evolution and to identify adaptations that affect pathogenicity or transmission. While single-nucleotide variations (SNVs) are commonly considered as driving virus adaption, RNA recombination events that delete or insert nucle...

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Detalles Bibliográficos
Autores principales: Jaworski, Elizabeth, Langsjoen, Rose M, Mitchell, Brooke, Judy, Barbara, Newman, Patrick, Plante, Jessica A, Plante, Kenneth S, Miller, Aaron L, Zhou, Yiyang, Swetnam, Daniele, Sotcheff, Stephanea, Morris, Victoria, Saada, Nehad, Machado, Rafael RG, McConnell, Allan, Widen, Steven G, Thompson, Jill, Dong, Jianli, Ren, Ping, Pyles, Rick B, Ksiazek, Thomas G, Menachery, Vineet D, Weaver, Scott C, Routh, Andrew L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478411/
https://www.ncbi.nlm.nih.gov/pubmed/34581669
http://dx.doi.org/10.7554/eLife.68479