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Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants
High-throughput genomics of SARS-CoV-2 is essential to characterize virus evolution and to identify adaptations that affect pathogenicity or transmission. While single-nucleotide variations (SNVs) are commonly considered as driving virus adaption, RNA recombination events that delete or insert nucle...
Autores principales: | Jaworski, Elizabeth, Langsjoen, Rose M, Mitchell, Brooke, Judy, Barbara, Newman, Patrick, Plante, Jessica A, Plante, Kenneth S, Miller, Aaron L, Zhou, Yiyang, Swetnam, Daniele, Sotcheff, Stephanea, Morris, Victoria, Saada, Nehad, Machado, Rafael RG, McConnell, Allan, Widen, Steven G, Thompson, Jill, Dong, Jianli, Ren, Ping, Pyles, Rick B, Ksiazek, Thomas G, Menachery, Vineet D, Weaver, Scott C, Routh, Andrew L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478411/ https://www.ncbi.nlm.nih.gov/pubmed/34581669 http://dx.doi.org/10.7554/eLife.68479 |
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