Multi-syndrome, multi-gene risk modeling for individuals with a family history of cancer with the novel R package PanelPRO

Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models focus on a few specific syndromes; however, recent evidence from multi-gene panel testing shows that many sy...

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Detalles Bibliográficos
Autores principales: Lee, Gavin, Liang, Jane W, Zhang, Qing, Huang, Theodore, Choirat, Christine, Parmigiani, Giovanni, Braun, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478415/
https://www.ncbi.nlm.nih.gov/pubmed/34406119
http://dx.doi.org/10.7554/eLife.68699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478415/
https://www.ncbi.nlm.nih.gov/pubmed/34406119
http://dx.doi.org/10.7554/eLife.68699

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