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Multi-syndrome, multi-gene risk modeling for individuals with a family history of cancer with the novel R package PanelPRO
Identifying individuals who are at high risk of cancer due to inherited germline mutations is critical for effective implementation of personalized prevention strategies. Most existing models focus on a few specific syndromes; however, recent evidence from multi-gene panel testing shows that many sy...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478415/ https://www.ncbi.nlm.nih.gov/pubmed/34406119 http://dx.doi.org/10.7554/eLife.68699 |