Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination

Schwann cell (SC) mitochondria are quickly emerging as an important regulator of myelin maintenance in the peripheral nervous system (PNS). However, the mechanisms underlying demyelination in the context of mitochondrial dysfunction in the PNS are incompletely understood. We recently showed that con...

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Detalles Bibliográficos
Autores principales: Della-Flora Nunes, Gustavo, Wilson, Emma R, Hurley, Edward, He, Bin, O'Malley, Bert W, Poitelon, Yannick, Wrabetz, Lawrence, Feltri, M Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478418/
https://www.ncbi.nlm.nih.gov/pubmed/34519641
http://dx.doi.org/10.7554/eLife.66278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478418/
https://www.ncbi.nlm.nih.gov/pubmed/34519641
http://dx.doi.org/10.7554/eLife.66278

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