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Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
Schwann cell (SC) mitochondria are quickly emerging as an important regulator of myelin maintenance in the peripheral nervous system (PNS). However, the mechanisms underlying demyelination in the context of mitochondrial dysfunction in the PNS are incompletely understood. We recently showed that con...
Autores principales: | Della-Flora Nunes, Gustavo, Wilson, Emma R, Hurley, Edward, He, Bin, O'Malley, Bert W, Poitelon, Yannick, Wrabetz, Lawrence, Feltri, M Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478418/ https://www.ncbi.nlm.nih.gov/pubmed/34519641 http://dx.doi.org/10.7554/eLife.66278 |
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