Bone Marrow Mesenchymal Stem Cells-Derived Exosomal miR-425-5p Inhibits Acute Myeloid Leukemia Cell Proliferation, Apoptosis, Invasion and Migration by Targeting WTAP

INTRODUCTION: Acute myeloid leukemia (AML) is a predominant blood malignancy with high mortality and severe morbidity. AML is affected by microRNAs (miRNAs) loaded in exosomes derived from bone marrow mesenchymal stem cells (BM-MSCs). MiR-425-5p has been reported to participate in different cancer m...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Khadka, Bijay, Wu, Jieying, Feng, Yashu, Long, Bing, Xiao, Ruozhi, Liu, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478487/
https://www.ncbi.nlm.nih.gov/pubmed/34594112
http://dx.doi.org/10.2147/OTT.S286326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478487/
https://www.ncbi.nlm.nih.gov/pubmed/34594112
http://dx.doi.org/10.2147/OTT.S286326

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