Cargando…

Bone Marrow Mesenchymal Stem Cells-Derived Exosomal miR-425-5p Inhibits Acute Myeloid Leukemia Cell Proliferation, Apoptosis, Invasion and Migration by Targeting WTAP

INTRODUCTION: Acute myeloid leukemia (AML) is a predominant blood malignancy with high mortality and severe morbidity. AML is affected by microRNAs (miRNAs) loaded in exosomes derived from bone marrow mesenchymal stem cells (BM-MSCs). MiR-425-5p has been reported to participate in different cancer m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ling, Khadka, Bijay, Wu, Jieying, Feng, Yashu, Long, Bing, Xiao, Ruozhi, Liu, Jiajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478487/ https://www.ncbi.nlm.nih.gov/pubmed/34594112 http://dx.doi.org/10.2147/OTT.S286326

Ejemplares similares

Bone Marrow Mesenchymal Stem Cells-Derived Exosomal miR-425-5p Inhibits Acute Myeloid Leukemia Cell Proliferation, Apoptosis, Invasion and Migration by Targeting WTAP [Retraction]
Publicado: (2022)

A Regulatory Loop Involving Notch and Wnt Signaling Maintains Leukemia Stem Cells in T-Cell Acute Lymphoblastic Leukemia
por: Zhang, Ling, et al.
Publicado: (2021)

MicroRNA-93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2
por: Huang, Jiwei, et al.
Publicado: (2021)

CircRNA circ_0000190 inhibits the progression of multiple myeloma through modulating miR-767-5p/MAPK4 pathway
por: Feng, Yashu, et al.
Publicado: (2019)

Human bone marrow mesenchymal stem cell-derived exosomes containing microRNA-425 promote migration, invasion and lung metastasis by down-regulating CPEB1
por: Wang, Guoqiang, et al.
Publicado: (2022)

WTAP-mediated m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis
por: You, Yunhao, et al.
Publicado: (2023)

MicroRNAs of bone marrow mesenchymal stem cell-derived exosomes regulate acute myeloid leukemia cell proliferation and apoptosis
por: Xu, Yi-Chuan, et al.
Publicado: (2020)

Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis
por: Barrera-Ramirez, Juliana, et al.
Publicado: (2017)

Oncogenic Long Noncoding RNA DARS-AS1 in Childhood Acute Myeloid Leukemia by Binding to microRNA-425
por: Dou, Binghua, et al.
Publicado: (2020)

P425: A MULTIDIMENSIONAL AND SPATIAL ANALYSIS REVEALS DISTINCT IMMUNE PHENOTYPES AND SECONDARY LYMPHOID ORGAN-RESEMBLING STRUCTURES IN THE BONE MARROW OF PEDIATRIC ACUTE MYELOID LEUKEMIA
por: Koedijk, Joost, et al.
Publicado: (2023)

Cancer cell-derived exosomal miR-425-3p induces white adipocyte atrophy
por: Liu, Anwen, et al.
Publicado: (2022)

FRI425 BIUXX
por: Mendonça Macedo, Daniel, et al.
Publicado: (2023)

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
por: Kumar, B, et al.
Publicado: (2018)

MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy
por: Yang, Chen, et al.
Publicado: (2018)

The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia
por: Ciciarello, Marilena, et al.
Publicado: (2019)

Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang
por: Zhou, Hong-Sheng, et al.
Publicado: (2016)

WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche
por: Jia, Gong-Xue, et al.
Publicado: (2020)

METTL3 regulates WTAP protein homeostasis
por: Sorci, Melissa, et al.
Publicado: (2018)

Bone marrow mesenchymal stem cell-derived exosomal LINC00847 inhibits the proliferation, migration, and invasion of Ewing sarcoma
por: Huang, Lu, et al.
Publicado: (2022)

7-Ketocholesterol Promotes Oxiapoptophagy in Bone Marrow Mesenchymal Stem Cell from Patients with Acute Myeloid Leukemia
por: Paz, Jessica Liliane, et al.
Publicado: (2019)

Discovery of proangiogenic CD44+mesenchymal cancer stem cells in an acute myeloid leukemia patient’s bone marrow
por: Cao, Huynh, et al.
Publicado: (2020)

Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
por: Kouzi, Farah, et al.
Publicado: (2019)

Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma
por: Quan, Jing, et al.
Publicado: (2018)

WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis
por: Liu, Jincheng, et al.
Publicado: (2023)

MiR-425 Promotes Migration and Invasion in Bladder Cancer by Targeting Dickkopf 3
por: Ning, Jin-zhuo, et al.
Publicado: (2020)

Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development
por: Yao, Yiyi, et al.
Publicado: (2021)

Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration
por: Huang, J C, et al.
Publicado: (2015)

Correction: Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells
por: Kouzi, Farah, et al.
Publicado: (2019)

Acute Myeloid Leukemia Causes Serious and Partially Irreversible Changes in Secretomes of Bone Marrow Multipotent Mesenchymal Stromal Cells
por: Sadovskaya, Aleksandra, et al.
Publicado: (2023)

PB1823: THE BONE MARROW MICROENVIRONMENT IN ACUTE MYELOID LEUKEMIA: THE ROLE OF MESENCHYMAL STEM CELLS AND THEIR IMPACT ON THE CLINICAL OUTCOME
por: Calabretta, Ludovica, et al.
Publicado: (2023)

Regulation of Malignant Myeloid Leukemia by Mesenchymal Stem Cells
por: Tan, Zhenya, et al.
Publicado: (2022)

Loss of WTAP Impairs Early Parthenogenetic Embryo Development
por: Hao, Jindong, et al.
Publicado: (2021)

Role of WTAP in Cancer: From Mechanisms to the Therapeutic Potential
por: Fan, Yongfei, et al.
Publicado: (2022)

The Emerging, Multifaceted Role of WTAP in Cancer and Cancer Therapeutics
por: Ju, Guomin, et al.
Publicado: (2023)

Re‐evaluation of konjac gum (E 425 i) and konjac glucomannan (E 425 ii) as food additives
por: Mortensen, Alicja, et al.
Publicado: (2017)

Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
por: Jin, Yi, et al.
Publicado: (2021)

WTAP Is Correlated With Unfavorable Prognosis, Tumor Cell Proliferation, and Immune Infiltration in Hepatocellular Carcinoma
por: Liang, Linjun, et al.
Publicado: (2022)

RNA N6‑methyladenosine methyltransferase WTAP promotes the differentiation of endothelial progenitor cells
por: Wu, Longyun, et al.
Publicado: (2023)

Remodeling of Bone Marrow Niches and Roles of Exosomes in Leukemia
por: Yamaguchi, Takanori, et al.
Publicado: (2021)

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
por: Forte, Dorian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u678lnf64ubt6t9nrslf3b3jor