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SCIGA: Software for large-scale, single-cell immunoglobulin repertoire analysis

BACKGROUND: B-cell immunoglobulin repertoires with paired heavy and light chain can be determined by means of 10X single-cell V(D)J sequencing. Precise and quick analysis of 10X single-cell immunoglobulin repertoires remains a challenge owing to the high diversity of immunoglobulin repertoires and a...

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Detalles Bibliográficos
Autores principales: Ye, Haocheng, Cheng, Lin, Ju, Bin, Xu, Gang, Liu, Yang, Zhang, Shuye, Wang, Lifei, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478610/
https://www.ncbi.nlm.nih.gov/pubmed/34585238
http://dx.doi.org/10.1093/gigascience/giab050