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Lysosomes in acute myeloid leukemia: potential therapeutic targets?

Lysosomes, since their discovery, have been primarily known for degrading cellular macromolecules. However, in recent studies, they have begun to emerge as crucial regulators of cell homeostasis. They are at the crossroads of catabolic and anabolic pathways and are intricately involved in cellular t...

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Detalles Bibliográficos
Autores principales: Rafiq, Sreoshee, McKenna, Sharon L., Muller, Sylviane, Tschan, Mario P., Humbert, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478647/
https://www.ncbi.nlm.nih.gov/pubmed/34462526
http://dx.doi.org/10.1038/s41375-021-01388-x