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Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness

Despite recent approval of targeted drugs for acute myeloid leukemia (AML) therapy, chemotherapy with cytosine arabinoside and anthracyclines remains an important pillar of treatment. Both primary and secondary resistance are frequent and associated with poor survival, yet the underlying molecular m...

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Detalles Bibliográficos
Autores principales: Grandits, Alexander Michael, Nguyen, Chi Huu, Schlerka, Angela, Hackl, Hubert, Sill, Heinz, Etzler, Julia, Heyes, Elizabeth, Stoiber, Dagmar, Grebien, Florian, Heller, Gerwin, Wieser, Rotraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478650/
https://www.ncbi.nlm.nih.gov/pubmed/33782537
http://dx.doi.org/10.1038/s41375-021-01224-2