Using simulated infectious disease outbreaks to inform site selection and sample size for individually randomized vaccine trials during an ongoing epidemic

BACKGROUND: Novel strategies are needed to make vaccine efficacy trials more robust given uncertain epidemiology of infectious disease outbreaks, such as arboviruses like Zika. Spatially resolved mathematical and statistical models can help investigators identify sites at highest risk of future tran...

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Detalles Bibliográficos
Autores principales: Madewell, Zachary J, Pastore Y Piontti, Ana, Zhang, Qian, Burton, Nathan, Yang, Yang, Longini, Ira M, Halloran, M Elizabeth, Vespignani, Alessandro, Dean, Natalie E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Design
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478719/
https://www.ncbi.nlm.nih.gov/pubmed/34218667
http://dx.doi.org/10.1177/17407745211028898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478719/
https://www.ncbi.nlm.nih.gov/pubmed/34218667
http://dx.doi.org/10.1177/17407745211028898

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