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Severe liver disease resembling PSC in mice with K5-Cre mediated deletion of Krüppel-like factor 5 (Klf5)

Chronic cholestatic liver diseases including primary sclerosing cholangitis (PSC) present a complex spectrum with regards to the cause, age of manifestation and histopathological features. Current treatment options are severely limited primarily due to a paucity of model systems mirroring the diseas...

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Detalles Bibliográficos
Autores principales: Bergström, Åsa, Gerling, Marco, Van Hul, Noémi, Fernández Moro, Carlos, Rozell, Björn, Toftgård, Rune, Sur, Inderpreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478727/
https://www.ncbi.nlm.nih.gov/pubmed/34117597
http://dx.doi.org/10.1007/s11248-021-00267-6