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Severe liver disease resembling PSC in mice with K5-Cre mediated deletion of Krüppel-like factor 5 (Klf5)
Chronic cholestatic liver diseases including primary sclerosing cholangitis (PSC) present a complex spectrum with regards to the cause, age of manifestation and histopathological features. Current treatment options are severely limited primarily due to a paucity of model systems mirroring the diseas...
Autores principales: | Bergström, Åsa, Gerling, Marco, Van Hul, Noémi, Fernández Moro, Carlos, Rozell, Björn, Toftgård, Rune, Sur, Inderpreet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478727/ https://www.ncbi.nlm.nih.gov/pubmed/34117597 http://dx.doi.org/10.1007/s11248-021-00267-6 |
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