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Characterizing temporal and spatial recruitment of systemically administered RPE65-programmed bone marrow-derived cells to the retina in a mouse model of age-related macular degeneration

PURPOSE: Previously, we reported that the intravenous injection of bone marrow-derived cells (BMDC) infected with lentivirus expressing the human RPE65 gene resulted in the programming of BMDC to promote visual recovery in a mouse model of age-related macular degeneration (AMD). The aim of this stud...

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Detalles Bibliográficos
Autores principales: Francelin, Carolina, Godoy, Juliana, Qi, Xiaoping, Silva, Juliete A. F., Grant, Maria B., Boulton, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478769/
https://www.ncbi.nlm.nih.gov/pubmed/34357416
http://dx.doi.org/10.1007/s00417-021-05358-y