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Characterizing temporal and spatial recruitment of systemically administered RPE65-programmed bone marrow-derived cells to the retina in a mouse model of age-related macular degeneration
PURPOSE: Previously, we reported that the intravenous injection of bone marrow-derived cells (BMDC) infected with lentivirus expressing the human RPE65 gene resulted in the programming of BMDC to promote visual recovery in a mouse model of age-related macular degeneration (AMD). The aim of this stud...
Autores principales: | Francelin, Carolina, Godoy, Juliana, Qi, Xiaoping, Silva, Juliete A. F., Grant, Maria B., Boulton, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478769/ https://www.ncbi.nlm.nih.gov/pubmed/34357416 http://dx.doi.org/10.1007/s00417-021-05358-y |
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