Identifying Safety Thresholds for Immunosuppressive Drugs: Applying Insights from Primary Antibody Deficiencies to Mitigate Adverse Events in Secondary Antibody Deficiencies Using Mathematical Modeling of Preclinical and Early Clinical Data

Immunosuppressive drugs can alleviate debilitating symptoms of autoimmune diseases, but, by the same token, excessive immune suppression can result in an increased risk of infection. Despite the dangers of a compromised immune system, clear definitions of what constitutes excessive suppression remai...

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Detalles Bibliográficos
Autores principales: Kareva, Irina, Zutshi, Anup, Mateo, Cristina Vazquez, Papasouliotis, Orestis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Practical Application
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478771/
https://www.ncbi.nlm.nih.gov/pubmed/34328632
http://dx.doi.org/10.1007/s13318-021-00706-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478771/
https://www.ncbi.nlm.nih.gov/pubmed/34328632
http://dx.doi.org/10.1007/s13318-021-00706-z

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