Single-dose of Synthetic MicroRNA-199a or MicroRNA-149 Mimic Does Not Improve Cardiac Function in a Murine Model of Myocardial Infarction

Intramyocardial injection of synthetic microRNAs (miRs) has recently been reported to be beneficial after myocardial infarction (MI). We conducted a randomized blinded study to evaluate the efficacy and reproducibility of this strategy in a mouse model of reperfused MI using rigorous methodology. Mi...

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Detalles Bibliográficos
Autores principales: Nong, Yibing, Guo, Yiru, Gumpert, Anna, Li, Qianhong, Tomlin, Alex, Zhu, Xiaoping, Bolli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478849/
https://www.ncbi.nlm.nih.gov/pubmed/34287784
http://dx.doi.org/10.1007/s11010-021-04227-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478849/
https://www.ncbi.nlm.nih.gov/pubmed/34287784
http://dx.doi.org/10.1007/s11010-021-04227-w

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