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Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE

SLC4 transporters play significant roles in pH regulation and cellular sodium transport. The previously solved structures of the outward facing (OF) conformation for AE1 (SLC4A1) and NBCe1 (SLC4A4) transporters revealed an identical overall fold despite their different transport modes (chloride/bica...

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Detalles Bibliográficos
Autores principales: Wang, Weiguang, Tsirulnikov, Kirill, Zhekova, Hristina R., Kayık, Gülru, Khan, Hanif Muhammad, Azimov, Rustam, Abuladze, Natalia, Kao, Liyo, Newman, Debbie, Noskov, Sergei Yu., Zhou, Z. Hong, Pushkin, Alexander, Kurtz, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478935/
https://www.ncbi.nlm.nih.gov/pubmed/34584093
http://dx.doi.org/10.1038/s41467-021-25998-2