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Receptor tyrosine kinase ROR1 ameliorates Aβ(1–42) induced cytoskeletal instability and is regulated by the miR146a-NEAT1 nexus in Alzheimer’s disease
Alzheimer’s disease (AD) involves severe cytoskeletal degradation and microtubule disruption. Here, we studied the altered dynamics of ROR1, a Receptor Tyrosine Kinase (RTK), and how it could counter these abnormalities. We found that in an Aβ(1–42) treated cell model of AD, ROR1 was significantly d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479066/ https://www.ncbi.nlm.nih.gov/pubmed/34584188 http://dx.doi.org/10.1038/s41598-021-98882-0 |