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Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

DNA repair promotes the progression and recurrence of glioblastoma (GBM). However, there remain no effective therapies for targeting the DNA damage response and repair (DDR) pathway in the clinical setting. Thus, we aimed to conduct a comprehensive analysis of DDR genes in GBM specimens to understan...

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Detalles Bibliográficos
Autores principales: Yang, Wen-Bin, Wu, An-Chih, Hsu, Tsung-I, Liou, Jing-Ping, Lo, Wei-Lun, Chang, Kwang-Yu, Chen, Pin-Yuan, Kikkawa, Ushio, Yang, Shung-Tai, Kao, Tzu-Jen, Chen, Ruei-Ming, Chang, Wen-Chang, Ko, Chiung-Yuan, Chuang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479077/
https://www.ncbi.nlm.nih.gov/pubmed/34584069
http://dx.doi.org/10.1038/s41419-021-04182-w