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Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability
Genetic polymorphisms in DNA damage repair and tumor suppressor genes have been associated with increasing the risk of several types of cancer. Analyses of putative functional single nucleotide polymorphisms (SNP) in such genes can greatly improve human health by guiding choice of therapeutics. In t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479081/ https://www.ncbi.nlm.nih.gov/pubmed/34584144 http://dx.doi.org/10.1038/s41598-021-98547-y |