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Pathogenic genetic variants from highly connected cancer susceptibility genes confer the loss of structural stability

Genetic polymorphisms in DNA damage repair and tumor suppressor genes have been associated with increasing the risk of several types of cancer. Analyses of putative functional single nucleotide polymorphisms (SNP) in such genes can greatly improve human health by guiding choice of therapeutics. In t...

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Detalles Bibliográficos
Autores principales: Reza, Mahjerin Nasrin, Ferdous, Nadim, Emon, Md. Tabassum Hossain, Islam, Md. Shariful, Mohiuddin, A. K. M., Hossain, Mohammad Uzzal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479081/
https://www.ncbi.nlm.nih.gov/pubmed/34584144
http://dx.doi.org/10.1038/s41598-021-98547-y