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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

Existing preclinical methods for acquiring dissemination kinetics of rare circulating tumor cells (CTCs) en route to forming metastases have not been capable of providing a direct measure of CTC intravasation rate and subsequent half-life in the circulation. Here, we demonstrate an approach for meas...

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Detalles Bibliográficos
Autores principales: Hamza, Bashar, Miller, Alex B., Meier, Lara, Stockslager, Max, Ng, Sheng Rong, King, Emily M., Lin, Lin, DeGouveia, Kelsey L., Mulugeta, Nolawit, Calistri, Nicholas L., Strouf, Haley, Bray, Christina, Rodriguez, Felicia, Freed-Pastor, William A., Chin, Christopher R., Jaramillo, Grissel C., Burger, Megan L., Weinberg, Robert A., Shalek, Alex K., Jacks, Tyler, Manalis, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479082/
https://www.ncbi.nlm.nih.gov/pubmed/34584084
http://dx.doi.org/10.1038/s41467-021-25917-5