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Effects of Aβ-derived peptide fragments on fibrillogenesis of Aβ

Amyloid β (Aβ) peptide aggregation plays a central role in Alzheimer’s disease (AD) etiology. AD drug candidates have included small molecules or peptides directed towards inhibition of Aβ fibrillogenesis. Although some Aβ-derived peptide fragments suppress Aβ fibril growth, comprehensive analysis o...

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Detalles Bibliográficos
Autores principales: Abedin, Faisal, Kandel, Nabin, Tatulian, Suren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479085/
https://www.ncbi.nlm.nih.gov/pubmed/34584131
http://dx.doi.org/10.1038/s41598-021-98644-y