Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase

Nature forms S-S bonds by oxidizing two sulfhydryl groups, and no enzyme installing an intact hydropersulfide (-SSH) group into a natural product has been identified to date. The leinamycin (LNM) family of natural products features intact S-S bonds, and previously we reported an SH domain (LnmJ-SH)...

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Detalles Bibliográficos
Autores principales: Meng, Song, Steele, Andrew D., Yan, Wei, Pan, Guohui, Kalkreuter, Edward, Liu, Yu-Chen, Xu, Zhengren, Shen, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479088/
https://www.ncbi.nlm.nih.gov/pubmed/34584078
http://dx.doi.org/10.1038/s41467-021-25798-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479088/
https://www.ncbi.nlm.nih.gov/pubmed/34584078
http://dx.doi.org/10.1038/s41467-021-25798-8

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