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Loop Diuretics Inhibit Ischemia-Induced Intracellular Ca(2+) Overload in Neurons via the Inhibition of Voltage-Gated Ca(2+) and Na(+) Channels
One consequence of ischemic stroke is disruption of intracellular ionic homeostasis. Intracellular overload of both Na(+) and Ca(2+) has been linked to neuronal death in this pathophysiological state. The etiology of ionic imbalances resulting from stroke-induced ischemia and acidosis includes the d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479115/ https://www.ncbi.nlm.nih.gov/pubmed/34603048 http://dx.doi.org/10.3389/fphar.2021.732922 |